Alternative/ Predictive Methods
30 years of Alternative/Predictive Methods Development
For more than twenty years, L’Oréal has been committed to developing alternative/predictive methods for the cosmetic product safety and efficacy evaluation.

In partnership with universities, start-ups and industrial sectors (pharmaceutical, chemical, household), hundreds of scientists bring their efforts all together to provide new methods for innovation worldwide.

The group has invested over €665 million in international research centres and employs more than 100 scientists who work on alternative methods. We share all our findings with the Commission, other industries and the scientific community. In fact, our research enabled the replacement of all skin irritation tests on animals with an alternative method.

Five of our models have already been approved by international bodies and are sold throughout the world today, as replacement methods for testing corrosion, phototoxicity, genotoxicity and skin irritation. We are currently undergoing pre-validation for eye irritation. The results are just as conclusive for evaluating the effectiveness of our ingredients and helping in the formulation of our products.

  • In 1989, L’Oreal voluntarily stopped using animal testing for the evaluation of its entire range of finished products, 14 years before the regulatory deadline to do so.

  • In 2009, L’Oréal successfully met the first deadline introduced by the 7th amendment to the EU Cosmetics Directive that bans most ingredient tests. L’Oreal was able to meet the deadline thanks once again to its vast research into alternative testing methods.

  • As for 2013, the next deadline for a ban on all remaining cosmetic ingredients tests, L’Oréal is working relentlessly with members of the cosmetics industry, as well as across different industry sectors and with the European Commission.


Only the cosmetics sector has undertaken the enormous endeavour to develop alternative methods to replace animal testing. L’Oréal is hopeful these efforts will achieve a future without animal testing

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J. Cotovio, Predictive Models & Methods


Tissue Engineering & Alternatives Methods

Agrostat 2016 is the 14th Symposium on Statistical Methods for the Food Industry (Lausanne, Switzerland 21st-24th March 2016). L’Oréal Research & Innovation was proud to sponsor this congress.

Discover our contributions for Sensometrics, Chemometrics and Risk & Process oral sessions.